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Ім'я файлу: Антиангінальні для студентів.docx
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Amiodaronum.

  • Novocainamidum.

  • Chinidini sulfas.

  • Disopyramidum.




    1. A patient with angina pectoris developed bronchospasm after taking antianginal medicine. What drug could provoke it?

      1. Nifedipinum.

      2. Nitroglycerinum.

      3. Sustac-forte.

      4. Dipyridamolum.

      5. Propranololum.




    1. A doctor recommended a patient, who had an acute myocardial infarction, to take acidum acetylsalicylicum in the dose of 0.25 g once per 2 - 3 days during 3 - 4 months. What effect did the doctor count on?

      1. Antiaggregant.

      2. Antiinflammatory.

      3. Antipyretic.

      4. Analgesic.

      5. Vasodilative.




    1. A patient with ischemic disease has not informed the doctor that he had attacks of bronchospasm. The doctor prescribed a drug, which has made the attacks of angina pectoris less frequent, but the attacks of bronchospasm have become more frequent. What medicine has been prescribed?

      1. Atenololum.

      2. Propranololum.

      3. Verapamilum.

      4. Diltiazemum.

      5. Nitrosorbidum.




    1. A 53-year-old woman suffers from heart attacks. The patient is bothered by severe chest pain, arrhythmia and short breath. What drug is the most expedient for prescription in this case to provide first aid?

      1. Nitrosorbidum.

      2. Nitroglycerinum.

      3. Amiodaronum.

      4. Propranololum.

      5. Sustac-forte.




    1. Acidum acetylsalicylicum (75 mg, daily) is prescribed to a patient, who had a myocardial infarction. With what purpose is the drug prescribed?

      1. Reduction of body temperature.

      2. Reduction of inflammation.

      3. Reduction of pain.

      4. Dilatation of coronary vessels.

      5. Reduction of thrombocytes aggregation.




    1. A 50-year-old man has appeal led to a doctor with complaints of chest pain, which occurs in the street, on his way to work, during physical activity. He has been ill for one year. The pain disappeared after taking validol, but recently its application has become inefficient. What drug should be prescribed?

      1. Natrii chloridum.

      2. Metoprololum.

      3. Octadinum.

    2. D.Clophelinum.

      1. Salbutamolum.




    1. A 65-year-old patient felt retrosternal pain while waiting in a queue during the visit to a dermatologist. What drug is the most effective in this case?

      1. Cordiaminum.

      2. Validolum.

      3. Sustac-forte.

      4. Nitroglycerinum.

      5. Analginum.




    1. A drug in the form of aerosol was prescribed to a patient with angina pectoris. The patient had retrosternal pain and used an antianginal drug. The pain disappeared, but the patient began to complain of headache and vertigo. What drug has been used by the patient?

      1. Nitroglycerinum.

      2. Propranololum.

      3. Metoprololum.

      4. Validolum.

      5. Verapamilum.




    1. A patient who had been suffering from stable stenocardia was treated with anapriline in the dosage of 0,02 g 3 times a day. In a week the patient had felt better but began to complaint of difficulty of respiration. Specify which drug from the group of beta-adrenoblockers should be appointed instead anapriline.

      1. The antagonist of calcium – Verapamilum.

      2. Cardioselective beta-adrenobiocker – Metoprololum.

      3. Long acting drug of nitroglycerine – Sustac-forte.

      4. The antagonist of calcium –Nifediplnum.

      5. Organic nitrate – Nitrogiycerinum.




    1. Determine an antianginal agent by its pharmacological effect. It insignificantly improves coronary circulation (especially in subendocardial layers), but the main cause of elimination of stenocardia is dilation of peripheral veins and arteries, that leads to decrease of cardiac work and myocardial oxygen demand. Besides, it oppresses the central links of cardiostimulating reflexes.

      1. Amiodaronum.

      2. Phenihydinum.

      3. Nitrogiycerinum.

      4. Validolum.

    2. E Anaplilinum.




    1. A patient who had been suffering from stenocardia accompanied by cardiac arrhythmia (paroxysmal tachycardia) and arterial hypertension was admitted to the hospital. Specify antianginal drug and the group which it belongs to, which should be administered taking into account the patient's diseases.

      1. β-adrenoblocker – Anaprilinum.

      2. Organic nitrate – Nitroglycerinum.

      3. Myotropic coronarodilating agent – Carbocromenum.

      4. Caicium antagonist – Nifedipinum.

      5. Potassium channel activator - Nicorandilum.




    1. Indicate the nitroglycerin's drug with prolonged action

      1. Natrii nitroprussidum.

      2. Validolum.

      3. Amyl nitrite.

      4. Sustac-forte.

      5. Dipiridamolum.




    1. Indicate the drug which exerts antianginal action because of decrease of oxygen demand and increase of oxygen delivery to the myocardium.

      1. Nitrogiycerinum.

      2. Anapnlinum.

      3. Dipiridamolum.

      4. Talinololum

      5. Carbocromenum.




    1. Indicate the state which requires administration of nitroglycerine.

      1. Chronic cardiac insufficiency.

      2. Acute cardiac failure.

      3. Hypertensive crisis.

      4. An attack of stenocardia.

      5. Endarteritis obliterans.




    1. Indicate the drug which should be used in the attack of angina pectoris:

      1. Strophanthinum.

      2. Bemegridum.

      3. Nitrong

      4. Benzohexonium.

      5. Nitroglycerinum.




    1. Indicate the mechanism of action of nitroglycerine.

      1. Release of NO groups which activate guanylyl cyclase.

      2. Blockade of calcium channels.

      3. Blockade of adenosine receptors.

      4. Activation of adenylyl cyclase.

      5. Inhibition of phosphodiesterase.




    1. A patient with ischemic heart disease complaints of worsening of his state that is caused by overdosage of anti-anginal agent. What group of drugs can cause this state if it is known that concentration of methemoglobin in patients blood is increased?

      1. Beta-adrenoblockers.

      2. Organic nitrates.

      3. Blockers of calcium channels.

      4. Activators of potassium channels.

      5. Myotropic coronary dilators.




    1. After sublingual introduction of nitroglycerine its maximal concentration in blood is developed in:

      1. 1 minute.

      2. 15 minutes.

      3. 2-5 minutes.

      4. 30 minutes.

      5. 1 hour.




    1. Why are the tablets of nitroglycerine introduced sublingually only?

      1. The substance is destroyed under the action of gastric juice.

      2. The substance is badly absorbed in the gastrointestinal tract

      3. The substance operates reflexly from oral cavity receptors.

      4. The substance is being considerably destroyed during its first passage through the fiver.

      5. It causes less side-effect in such way of introduction.




    1. Indicate the calcium channel blocker which belongs to the group of derivatives of phenylalkylamines:

      1. Nifedipinum.

      2. Diltiazemum.

      3. Nicardipinum.

      4. Clentiazemum.

      5. Verapamilum.




    1. Among special hypolipidemic agents the most effective ones are those which block synthesis of endogenous cholesterol in the liver. What drug from listed below has such mechanism of action?

      1. Probucolum.

      2. Clofibratum.

      3. Cholestyraminum.

      4. Parmidinum.

      5. Lovastatinum




    1. A patient has the family hypercholesterolemia. Indicate the drug which may be used due to ability to inhibit the main enzyme of cholesterol synthesis?


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